Lee Meitzen Grue was born in Placquemine, Louisiana and has spent most of her life in New Orleans. In the early 1960s, she began reading her poetry at The Quorum Club, the first non-segregated coffee house in the South. Here she met jazz flautist Eluard Burt, with whom she collaborated over many years, including on the jazz poetry CD Live! on Frenchmen Street. Grue founded the New Orleans Poetry Forum, an independent group of poets that sponsored workshops and readings, in 1972, and directed and maintained the Forum until 1990. For many years she promoted poetry readings at her home, establishing there the Backyard Poetry Theater. In 1982, she founded the international independent literary journal, The New Laurel Review, which is still active today. In 2018 she received the Albert Nelson Marquis Lifetime Achievement Award.